Now I am going to dive into the stuff I am really looking forward to and I was not doing for years - GUI development. Therefore I first asked on #python and I really got the impression really quickly that Tkinter is out, wxPython rules. Ok the result of this article came early. My decision was taken quickly too.
Anyway I wanted more proof here it is, a nice short summary of Tkinter vs. wxPython. About Tkinter there is said "Probably a dead-end technology, as toolkits such as wxPython gain mindshare." ok that's enough, I am convinced.
Next of course I was looking for tools to build the GUI. I always want to see results first, I learn best on the job.
On #python someone suggested boa constructor (cool name!). It is not as straight forward as I expected it, but I might learn.
Within the examples of wxPython comes XRCed a simple but not WYSIWYG editor but somehow easy to catch up with. And for being a beginner with wxPython I was right away impressed of what it can do and how good it looks, this app is written with wxPython of course.
In the article mentioned above I read about wxDesigner. I don't know it yet, but it looks good. You have to buy a license, until you didn't you can not save. Let's see.
There are some more wxGlade, PythonCard and Spe.